Clay Siegall leads Seattle Genetics to first viable ADC

For decades, the only option for cancer treatment was chemotherapy, radiation and surgery. All of these treatments had horrible side effects, often leaving the patient permanently scarred and disabled. But that all began to change in the ‘90s, when a number of new types of drugs and cancer treatments started coming on the scene. This new generation of cancer treatment, broadly referred to as targeted cancer therapy, promised to drastically improve the efficacy of treatments and reduce side effects dramatically.


One of the key figures in the development and introduction of this new class of drugs is a man named Clay Siegall. Dr. Siegall has a long history as a cancer researcher. With an MS from the University of Maryland in biology as well as a PhD in genetics from George Washington University, he had worked for over 15 years for a string of research firms, including the National Cancer Institute and Bristol-Myers Squibb. He was working as a senior researcher at the latter firm, when he decided to strike out on his own, working on the development of an all new class of targeted cancer therapy known as antibody drug conjugates.


in 1998, Dr. Siegall founded Seattle Genetics, the first company dedicated solely to the development of antibody drug conjugates. With only a few million dollars in venture capital, Dr. Siegall began working feverishly with just a skeletal crew of researchers and office staff. But he quickly grew the company into a multi-billion-dollar firm, having one of the largest IPOs in biotech history in 2001. Over the next 10 years, Seattle Genetics would go on to develop nearly 20 different antibody drug conjugate product lines. They also developed a large number of proprietary processes for the synthesis of a large number of antibody drug conjugate drugs and other types of cancer treatments.


In 2011, Seattle Genetics had its first FDA approval. The drug called ADCetris was approved by the FDA for the treatment of refractory non-Hodgkin’s lymphoma. This was a truly game-changing development in the treatment of that disease. ADCetris went on to save thousands of lives, giving those with non-Hodgkin’s lymphoma who had tried all other treatments and we’re unresponsive to them and new lease on life.


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JHSF and Their Boss José Auriemo Neto Reshaping the World

For most people, José Auriemo Neto’s name is not well known. But people from Brazil have certainly heard of him. His company JHSF works in real estate. The projects include apartments and other residential properties as well as commercial lots.

All Projects Start Small

They have spent time researching the market and going after various new development options that bring in revenue. They are not only re-shaping the market but also Brazil. At first, the company only developed residential properties in the different neighborhoods. Later they shifted their attention to projects that would continue bringing in revenue after the refurbishment was finished.

The company itself started its work in 1972 under the leadership of Fabio Auriemo from Brazil. They worked on smaller projects before the company could expand. At the moment the company has projects in Brazil, Uruguay as well as the US.

In the United States, the company has buildings in New York City. They also invested in development in Uruguay which is now a residential project in Las Piedras in Punta del Este.

Taking Risks to Grow

One of the projects JHSF worked on was the Shopping Metro Santa Cruz. It was the first shopping center in Brazil that also had its subway station.

José Auriemo Neto was the overseer of one of the first retail developments the company took on. It was a big deal since they had secured a contract with the retail giants such as Hermes and Pucci.

The luxury brands were looking into expanding to Brazil, and JHSF saw a new investment option. JHSF also secured a contract with Jimmy Choo, another business giant seeking to broaden the trade in Brazil. These contracts mostly helped to raise the prestige of the company. It also elevated the shopping center to the next level.

Leading by Example

José Auriemo Neto graduated from Fundação Armando Álvares Penteado University in Brazil. He began his career with JHSF in 1993 and started gathering real estate experience straight away. He also participated in founding Parkbem, a parking lot managing company to add to the company’s retail empire.

He leads by example and works hard to pursue different new projects the company could invest in further reshaping the real estate market in the world.

A Hearty Dinner for Two

This beneful commercial ( is a heart warming scene of dog and dog-mom eating dinner together. While the dog enjoys his bowl of Beneful Original, he observes his mom eating nothing but crackers and a cheese stick. Nevertheless, this dog is not about to let his bowl of delicious food go to waste. He continues gobbling while he thinks about the wholesome flavors he gets out of every bite. With such an exciting bowl waiting for him every night at dinner, it’s easy to enjoy his meal with his mom. While they have different tastes, the love these two have for eachother is obvious.

Andrew Rolfe Works With The Leadership Of The Ubuntu Fund To Raise More Resources

The Ubuntu Fund is a renowned organization that has been supporting disadvantaged children in the society. Over the years, they have helped over 400,000 children. When Jacob Lief founded the organization, it was only focusing on provision of education. However, the management of the Fund realized that students were not realizing their full potentials in class. To this end, they decided to undertake a comprehensive research. They found that HIV and hunger was hampering many children from going to school and concentrating on their studies. The leadership of the Fund started providing the students with nutrition and healthcare services. Today, there is a high enrollment and many children are doing exceptionally well in their studies.

Notably, the Fund runs a school campus in Port Elizabeth, South Africa. At the institution, the management of the same developed an innovative program. This program seeks to support all children from when they join the school until when they commence their careers. Recently, the Fund decided to hold a gala dinner in London. 300 guests graced the auspicious occasion. Andrew Rolfe ensured that the guests were well entertained. Moreover, he made sure that each guest was served with the meal of his or her choice. The Fund expected to raise £600,000. To their surprise, they were able to raise over £603,000. During the occasion Sinesipho Rabidyani said that she is a proud beneficiary of the Fund’s scholarship. Her story of how her father’s drinking behavior affected her childhood touched most of the guests.

These funds shall be put into good use. The management of the Fund said that they would expand their campus and construct a large pediatric clinic. The Ubuntu Fund shall use the extra money to enroll more needy children in the society.

About Andrew Rolfe

Andrew has been serving as the chairman of the organization. He has also been rendering his services for TowerBook as the managing partner. Andrew is a graduate of Harvard University. Rolfe has gained extensive management experience by virtue of working for different leading entities.

In the past, he worked for the Gap. As the president of the institution’s international division, Andrew expanded the company’s operations abroad. Rolfe has also worked for Pret A. Manger and Booker Foodservice. He is credited for enhancing the growth of these companies through his visionary leadership.


Madison Street Capital Leaders in Finance and Investment Banking

Located in Chicago, Illinois, Madison Street Capital has developed an impressive reputation among those in the financial world. This financial organization helps businesses reach their financial goals. Throughout the business world, they help clients in achieving financial goals by obtaining new credit sources. Madison Street Capital helps customers understand and negotiate complex mergers and acquisitions. Whether getting an open line of credit or understanding the complex process of mergers and acquisitions; Madison Street Capital is there to help corporations succeed. Learn more:


Through the years Madison Street Capital acquired several prestigious awards. Anthony Marsala, co-founder of Madison Street Capital, received the 40 under Forty Award. This award gives top honors to those forty and under who possess unique talents and are outstanding in the financial world. The award honors those forty and under who are impressive leaders in the business world. In 2017, Madison Street Capital won the Turnaround Award; competing among over 350 rivals and peers in the business world. They received the award for their ability in restructuring a financial transaction worth approximately twenty-five million dollars. Madison Street Capital is an impressive organization, well-known for its philanthropic work. Contributing to both the Red Cross and United Way, they also encourage their associates to give to charity. The Madison Street Capital reputation remains in place; putting the organization at the top of the financial world. Learn more:


The investment banking firm Madison Street Capital originated in Chicago, Illinois. Their commitment to success combined with outstanding leadership assists various companies involved in strategic financial transactions. Their goal is providing financial services benefiting both their clientele and investors. Whether buying or selling a business, they are the preferred experts in the world of investment banking. Well known in the United States, they are established in Europe, Africa, and Asia. Learn more:


Madison Street Capital is recognized as an accomplished leader in the world of business finance. However, they are also considered experts in estate and tax planning. Whether opening a line of credit or selling a business, Madison Street Capital is the investment banking company preferred by corporations and financial experts through throughout the world. Learn more:


Sustainable, Environmentally Friendly, Waiākea

The state of Hawaii has always taken pride in the natural beauty that surrounds their land. The beautiful state speaks the language of nature, with some of the best that mother earth as to offer. The people living in Hawaii believe in having the highest amount of respect for the land and the place that they come from, and believe it to be one of the most important factors of Hawaiian culture.

When it comes to the products that this state puts out, the people always try to make sure that they are sustainable and do not cause any harm to nature. Waiākea Bottled Water is one excellent example of a product that the beautiful state has put out. The company making Waiākea knows the importance of the environment to the people of Hawaii and go to great lengths to ensure that they can do their bit to preserve it. The people at Waiākea have been actively involved with numerous movements, and environment protection acts so that they can ensure that the relationship that the people share with the earth is left untarnished.

Waiākea is one of the extremely few companies in the entire world that puts in a lot of effort in their packaging. Waiākea bottles are made using only the highest grade of recycled plastic, which causes less harm to the environment. All of the bottles that they put out can once again be recycled after use.

But why would a company go to such great lengths to ensure that the state of Hawaii is preserved? Well, the answer is simple – it is because the water that Waiākea puts in their bottles is sourced from the natural water bodies that are present in the state. Since Waiākea is taking something from the land, it sees it as only fair to give back to them as well. Most of the water that Waiākea uses comes from the eastern part of the state, near the Mauna Loa Volcano. Most of this water in these water bodies comes from rainwater and melted snow. Through proper rain water harvesting and purification, Waiākea has found new and sustainable ways to give this valuable life force to the people drinking their water.


Learn more about Waiakea’s water here!

The Driving Force at AXA Advisors

Successful business entities require dedicated leadership, mentorship of young professionals, customer centered operations, and market oriented products, a workable strategy and a business plan. At AXA Advisors, Vincent Parascandola has been instrumental in the realization of the company’s objectives. AXA Group is a respectable financial company that specialize on wealth management and financial protection services.

Vincent is an alumnus of Xaverian High School class of 1979, and he later joined the Pace University- Lubin School of Business in the Greater New York City Area and graduated with a Bachelor of Science (Computer Science) in 1983. His career began as a systems analyst at Irving Trust Company in 1986, and two years later he joined Prudential Insurance as an agent where he received the National Rookie of the Year award. In 1990 he joined The MONY Group as a financial professional, and within a span of 15 years, he rose through the ranks in different managerial positions starting from the sales manager, managing director and finally field vice president of the group.

Vincent left The MONY Group and in May 2005 he joined AXA Equitable as the executive vice president and later he was appointed as the president of the Advantage Group and president of the Northern Division of AXA Equitable. Through his committed and excellent performance, he was appointed as the president, Continental Division of AXA Equitable where he was in charge of branch offices in California, Hawii and the Northeast part of the country.

Three years later he became the chief sales officer and president – Continental Division of AXA Equitable and in October 2004 he became the senior vice executive president of the same company where he currently works. His responsibilities include; recruiting and training new advisors of the firm, growth and development of over 255 financial professionals in New Jersey.

Vincent Parascandola has over 25 years ‘of experience in the financial sector and he is the driving force behind the tremendous performance of the firm. Under his leadership at AXA Advisors, the retail’s division of AXA Group, it has expanded its branches to about 43 branches around the country and he has contributed immensely tothe Group’s non-banking assets valued at $1.5 trillion.

How Tammy Mazzocco has been Helping Homeowners Benefit from Ohio’s Lucrative Real Estate Market

Sellers have greater chances of earning profits from Ohio’s real estate industry. While the industries in other U.S. states have been on the rise, Ohio’s real estate sector has been characterized by an increase in home values and demands. To be precise, a condo or a decent home in Central Ohio is priced at $199,950. This price is as a result of an 8.1 percent increase from last year. You can visit LinkedIn for the details.

Besides the increase in home values, home builders are also planning or constructing several developmental projects meant to change Ohio’s real estate sector. For instance, a home builder recently announced grand plans to build more than 240 homes in New Albany, Ohio before this year ends. Regarding tourist attraction, Ohio is considered as one of the desirable places that Americans wish to live. This is because the cost of living in this state is affordable. Ohio’s tech sector has been on a constant rise hence increasing job opportunities in the state. The Ohio public school system has also been critically acclaimed. Check out Ideamensch to know more.

About Tammy Mazzocco

One of the professionals who have been praised by Ohio home buyers and residents is Tammy Mazzocco. She is usually praised for her exceptional ability to help home buyers find high-quality homes. As she pursued her professional career in the lucrative industry, Tammy Mazzocco has always been part of the business community. She has extensive knowledge of the trends both local and national markets. This knowledge enables her to give clients advice on getting best homes and great deals.

Tammy Mazzocco stands out from other real estate agents working in Ohio based on her passion for treating customers like family. Her long career in the sector enabled her to understand all procedures involved in finalizing a home sale. She also works hard to ensure that all her customers get the best experience possible.

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OSI Group Promises Full Commitment To Sustainability Standards After Release Of Their Global Sustainability Report

OSI Group released its Global sustainability report for year 2016/2017 whereby it outlines the sustainability performance of the company’s operations across the world. Some of the things detailed in this report include the progress that the company has made in its most prioritized areas that concern the environment, social responsibility and a sustainable supply chain. Sustainable supply chain gives emphasis to food safety and quality as well as strict standards on animal welfare. Here are some of the high points that are included in the report:

• OSI Food Solutions facilities that are located in Europe attained their ISO14001 certification. This is a great achievement for the company because this certification is among the top most authoritative standards for environmental management in the world.

• OSI North America donated over 252,000 lbs of food to Feeding America from their amenities in the year 2015 so as to sustain the food banks provided by the network. Within the same year, GenOSI also donated over 55,000 lbs. of food in the Philippines to assist in feeding the homeless children in the country.

• OSI Group also sponsors animal welfare campaigns, training sessions, and workshops as part of their continuous support and commitment towards improving and creating awareness of important issues in global supplier networks and organizations.

David G. McDonald said that the group would hold their commitment to conduct business more sustainability and responsibly. David serves OSI Group as the President and Chief Operating Officer, and he assured consumers that they would continue to progress their responsible business practices. He added that they are doing this to ensure that they achieve operational efficiencies that enhance the lives of employees, sustain environmental resources and build their global communities. David McDonald says that as a company they are proud to have achieved all that, and they are enthusiastic to share the sustainability report to prove their actions.

OSI’s 2016/17 sustainability report summarizes their future initiatives to attain sustainability objectives among other generalized goals. The company has outlined several goals that they wish to achieve by the year 2020, and these include reducing energy and water intensity by 10 percent.

Customized Financial Services Provider Based in Texas

Nexbank’s CEO and President, John Holt, recently attended the Texas Bankers Associations 5th annual conference held in New Orleans, Louisiana. John Holt was invited to be one of the panelists and in the banker panel discussion that followed, John Holt was asked to speak on the reinvention of community banking and how the competitors in the field of banking can take the lead by using innovation as a tool.

The Annual Strategic Opportunities and M&A Conference is held every year and is attended by the noted dignitaries from the world of banking and finance. Many reputed consultants, advisors, and bankers attend this summit. The conference is not only useful in bringing together personalities to discuss on various issues that infect the bank and finance industry, but also provide the panelists and members to network on a positive note. It helps in providing the perfect platform for gaining new accounts and for merger and acquisition.

Nexbank is one of the oldest banks in Texas and also the thirteenth largest in the state. Nationally, the rank of the bank stands tall at 200. The bank operates through its three primary segments, including the commercial banking, mortgage banking, and institutional services. The company offers personalized services to its clients, and the customized nature of the services helps in ensuring that the customers are satisfied.

Nexbank is also the member of FDIC. The Nexbank has grown exponentially over the years and having started with just four employees, today the bank has close to 90 employees working for the bank. The bank has a total of 4 branches in the state of Texas and offers real estate investors and financial institutions with a broad range of financial services. The bank continues to add new services to its service portfolio in its aim to become a comprehensive service provider in the banking industry.